Mapping Post-Translational Modifications of de Novo Purine Biosynthetic Enzymes: Implications for Pathway Regulation.

Liu, Chunliang; Knudsen, Giselle M; Pedley, Anthony M; He, Jingxuan; Johnson, Jared L; Yaron, Tomer M; Cantley, Lewis C; Benkovic, Stephen J

Liu, Chunliang; Knudsen, Giselle M; Pedley, Anthony M; He, Jingxuan; Johnson, Jared L; Yaron, Tomer M; Cantley, Lewis C; Benkovic, Stephen J.

Affiliation

Liu C; Department of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
Knudsen GM; Department of Pharmaceutical Chemistry , University of California San Francisco Mass Spectrometry Facility , San Francisco , California 94158 , United States.
Pedley AM; Department of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
He J; Department of Chemistry , The Pennsylvania State University , University Park , Pennsylvania 16802 , United States.
Cantley LC; Department of Medicine , Beth Israel Deaconess Medical Center , Boston , Massachusetts 02115 , United States.
Benkovic SJ; Department of Systems Biology , Harvard Medical School , Boston , Massachusetts 02115 , United States.

J Proteome Res ; 18(5): 2078-2087, 2019 05 03.

Article de En | MEDLINE | ID: mdl-30964683

Sujet(s)
Mots clés

AKT; PTM; de novo purine biosynthesis; metabolism; phosphorylation; post-translational modification

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Purines / Cartographie peptidique / Maturation post-traductionnelle des protéines / Protéomique / Protéines proto-oncogènes c-akt / Amidophosphoribosyltransferase Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: J Proteome Res Sujet du journal: BIOQUIMICA Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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