Nonsaponin fraction of Korean Red Ginseng attenuates cytokine production via inhibition of TLR4 expression.

Ahn, Huijeong; Han, Byung-Cheol; Kim, Jeongeun; Kang, Seung Goo; Kim, Pyeung-Hyeun; Jang, Kyoung Hwa; So, Seung Ho; Lee, Seung-Ho; Lee, Geun-Shik

Ahn, Huijeong; Han, Byung-Cheol; Kim, Jeongeun; Kang, Seung Goo; Kim, Pyeung-Hyeun; Jang, Kyoung Hwa; So, Seung Ho; Lee, Seung-Ho; Lee, Geun-Shik.

Affiliation

Ahn H; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea.
Han BC; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea.
Kim J; Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon, Republic of Korea.
Kang SG; College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon, Republic of Korea.
Kim PH; Division of Biomedical Convergence, College of Biomedical Science, Kangwon National University, Chuncheon, Republic of Korea.
Jang KH; Department of Molecular Bioscience, School of Biomedical Science, Kangwon National University, Chuncheon, Republic of Korea.
So SH; Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon, Republic of Korea.
Lee SH; Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon, Republic of Korea.
Lee GS; Korea Ginseng Research Institute, Korea Ginseng Corporation, Daejeon, Republic of Korea.

J Ginseng Res ; 43(2): 291-299, 2019 Apr.

Article de En | MEDLINE | ID: mdl-30976167

Mots clés

Alum, aluminum potassium sulfate; BMDMs, bone marrowderived macrophages; Cytokine; HKST, heat-killed Salmonella typhimurium; IL, interleukin; Korean Red Ginseng extracts; LB, Luria-Bertani; LCCM, L929 cell-conditioned medium; LPS, lipopolysaccharide; Lys, lysate; MSU, monosodium urate crystal; NF-kB, nuclear factor kappa-light-chain-enhancer of activated B cells; NLRP3, (NOD)2-like receptor protein 3; NOD, nucleotide-binding and oligomerization domain; NS, nonsaponin fraction; Non, nontreatment; Nonsaponin fraction; PECs, peritoneal exudate cells; Peritonitis; RGE, Korean Red Ginseng extracts; SF, saponin fraction; Sup, supernatant; TLR4; TLRs, toll-like receptors; ip, intraperitoneally

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Prognostic_studies Langue: En Journal: J Ginseng Res Année: 2019 Type de document: Article Pays de publication:

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