[Depressive symptoms in early rheumatoid arthritis : Within the rheumatism network ADAPTHERA]. / Depressive Symptomatik bei früher rheumatoider Arthritis : Innerhalb des Rheumanetzwerks ADAPTHERA.
Z Rheumatol
; 78(7): 670-676, 2019 Sep.
Article
de De
| MEDLINE
| ID: mdl-31016369
ABSTRACT
BACKGROUND AND OBJECTIVE:
For patients with established rheumatoid arthritis and also early arthritis an increased prevalence of depression has been described. For a better understanding of depression in early arthritis patients, depression prevalences of a German early arthritis cohort were examined, with a focus on disease activity, anti-CCP status, disease duration and functional capacity over a period of 2 years. MATERIAL ANDMETHODS:
The evaluation was based on the early arthritis cohort ADAPTHERA from Rhineland-Palatinate. The inclusion criterion was a symptom duration before diagnosis of a maximum of 1 year. Data from the disease activity score 28 (DAS28), the Health Assessment Questionnaire (HAQ, functional status), the WHO-5 Well-Being Index (WHO-5, well-being and depressive symptoms) and the Patient Health Questionnaire-9 (PHQ-9, depressive symptoms) were collected.RESULTS:
At the beginning, 43.5% of patients had depressive symptoms (WHO-5â¯> 28). After the 2 year follow-up the percentage of patients with depressive symptoms had reduced to 20.8%. Correlations with disease activity according to DAS28 and the function of HAQ could be confirmed. There was no correlation between depressive symptoms and anti-CCP status (pâ¯= 0.431) or duration from symptom onset to diagnosis (pâ¯= 0.671).CONCLUSION:
Screening of early arthritis patients for the presence of depressive symptoms is of essential importance. Patients seem to be at high risk of developing depressive symptoms especially at the beginning of the disease and when showing high disability and poor results on disease activity score (DAS28 and visual analog scale).Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Polyarthrite rhumatoïde
/
Dépression
Type d'étude:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limites:
Humans
Langue:
De
Journal:
Z Rheumatol
Année:
2019
Type de document:
Article