Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A ( hTrkA) Inhibitors.

Subramanian, Govindan; Johnson, Paul D; Zachary, Theresa; Roush, Nicole; Zhu, Yaqi; Bowen, Scott J; Janssen, Ann; Duclos, Brian A; Williams, Tracey; Javens, Christopher; Shalaly, Nancy Dekki; Molina, Daniel Martinez; Wittwer, Arthur J; Hirsch, Jeffrey L

Subramanian, Govindan; Johnson, Paul D; Zachary, Theresa; Roush, Nicole; Zhu, Yaqi; Bowen, Scott J; Janssen, Ann; Duclos, Brian A; Williams, Tracey; Javens, Christopher; Shalaly, Nancy Dekki; Molina, Daniel Martinez; Wittwer, Arthur J; Hirsch, Jeffrey L.

Affiliation

Subramanian G; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Johnson PD; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Zachary T; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Roush N; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Zhu Y; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Bowen SJ; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Janssen A; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Duclos BA; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Williams T; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Javens C; Veterinary Medicine Research & Development (VMRD) , Zoetis, 333 Portage Street , Kalamazoo , Michigan 49007 , United States.
Shalaly ND; Pelago Bioscience , Banvaktsvägen 20 , 17148 Solna , Sweden.
Molina DM; Pelago Bioscience , Banvaktsvägen 20 , 17148 Solna , Sweden.
Wittwer AJ; Confluence Discovery Technologies , 4320 Forest Park Avenue , St. Louis , Missouri 63108 , United States.
Hirsch JL; Confluence Discovery Technologies , 4320 Forest Park Avenue , St. Louis , Missouri 63108 , United States.

ACS Chem Biol ; 14(6): 1205-1216, 2019 06 21.

Article de En | MEDLINE | ID: mdl-31059222

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur trkA / Inhibiteurs de protéines kinases Limites: Animals / Humans Langue: En Journal: ACS Chem Biol Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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