Help wanted: helper NLRs and plant immune responses.
Curr Opin Plant Biol
; 50: 82-94, 2019 08.
Article
de En
| MEDLINE
| ID: mdl-31063902
ABSTRACT
Plant nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins function as intracellular receptors in response to pathogens and activate effector-triggered immune responses (ETI). The activation of some sensor NLRs (sNLR) by their corresponding pathogen effector is well studied. However, the mechanisms by which the recently defined helper NLRs (hNLR) function to transduce sNLR activation into ETI-associated cell death and disease resistance remains poorly understood. We briefly summarize recent examples of sNLR activation and we then focus on hNLR requirements in sNLR-initiated immune responses. We further discuss how shared sequence homology with fungal self-incompatibility proteins and the mammalian mixed lineage kinase domain like pseudokinase (MLKL) proteins informs a plausible model for the structure and function of an ancient clade of plant hNLRs, called RNLs.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Maladies des plantes
/
Plantes
Limites:
Animals
Langue:
En
Journal:
Curr Opin Plant Biol
Sujet du journal:
BOTANICA
Année:
2019
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique