Qualitative identification of imidacloprid in postmortem animal tissue by gas chromatography-tandem mass spectrometry.
Toxicol Mech Methods
; 29(7): 511-517, 2019 Sep.
Article
de En
| MEDLINE
| ID: mdl-31070080
ABSTRACT
During an avian mass mortality event investigation at the National Fish and Wildlife Forensic Laboratory in Ashland, OR, imidacloprid became an insecticide of concern. A qualitative analytical toxicology screen of seeds, plucks (tongue, esophagus, and trachea), and ventricular contents was requested. A method for the extraction and qualitative analysis of the insecticide in animal tissues was therefore developed. The procedure relies on a combined Food Emergency Response Network (FERN) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) approach to sample extraction followed by qualitative analysis by gas chromatography-tandem mass spectrometry. Since imidacloprid is not amenable to the conditions of gas chromatography, a trimethylsilyl derivative was created and characterized. Proposed mechanisms for the creation of this derivative and its mass spectrum are described. The imidacloprid-trimethylsilyl (TMS) derivative was detected in all samples submitted.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Anatomopathologie vétérinaire
/
Oiseaux
/
Résidus de pesticides
/
Toxicologie médicolégale
/
Néonicotinoïdes
/
Composés nitrés
Type d'étude:
Diagnostic_studies
/
Qualitative_research
Limites:
Animals
Langue:
En
Journal:
Toxicol Mech Methods
Sujet du journal:
TOXICOLOGIA
Année:
2019
Type de document:
Article
Pays d'affiliation:
États-Unis d'Amérique