Design and analysis of stratified clinical trials in the presence of bias.

Hilgers, Ralf-Dieter; Manolov, Martin; Heussen, Nicole; Rosenberger, William F

Hilgers, Ralf-Dieter; Manolov, Martin; Heussen, Nicole; Rosenberger, William F.

Affiliation

Hilgers RD; Department of Medical Statistics, RWTH Aachen University, Aachen, Germany.
Manolov M; Department of Medical Statistics, RWTH Aachen University, Aachen, Germany.
Heussen N; Department of Medical Statistics, RWTH Aachen University, Aachen, Germany.
Rosenberger WF; Department of Biostatistics, Sigmund Freud University, Vienna, Austria.

Stat Methods Med Res ; 29(6): 1715-1727, 2020 06.

Article de En | MEDLINE | ID: mdl-31074333

Sujet(s)
Mots clés

Multi-center clinical trial; sample size; selection bias; stratified randomization; time-trend bias; type I error probability; weighted t test

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plan de recherche Type d'étude: Clinical_trials / Guideline / Prognostic_studies Limites: Humans Langue: En Journal: Stat Methods Med Res Année: 2020 Type de document: Article Pays d'affiliation: Allemagne

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