Favourable outcome of AIDS-related multi-centric central nervous system Epstein-Barr virus-associated smooth muscle tumour with surgery and adjuvant radiation therapy: a case study and literature review.
Int J STD AIDS
; 30(6): 605-609, 2019 05.
Article
de En
| MEDLINE
| ID: mdl-31074359
ABSTRACT
Epstein-Barr virus-associated smooth muscle tumour (EBV-SMT) is a unique condition which affects immunocompromised patients. We describe the favourable outcome of a patient with acquired immune deficiency syndrome (AIDS)-related multi-centric EBV-SMT involving the posterior fossa and spine treated with surgery and adjuvant volumetric modulated arc therapy comprising 50 Gy in 25 fractions to four sites initially to the brain and lumbar spine followed by sixth to ninth thoracic vertebrae (T6-T9) and sacrum a year later. Reported literature suggests that AIDS-related EBV-SMTs are more sensitive to radiotherapy. However, compliance to the highly active anti-retroviral therapy is paramount in preventing future recurrence. This case also emphasises the importance of multidisciplinary management in ensuring the best possible outcome.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Encéphale
/
Syndrome d'immunodéficience acquise
/
Tumeurs du système nerveux central
/
Tumeur du muscle lisse
/
Herpèsvirus humain de type 4
/
Radiothérapie adjuvante
/
Infections à virus Epstein-Barr
Type d'étude:
Clinical_trials
/
Diagnostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limites:
Adult
/
Humans
/
Male
Langue:
En
Journal:
Int J STD AIDS
Sujet du journal:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
Année:
2019
Type de document:
Article
Pays d'affiliation:
Singapour