Selective recognition of acetylcholine over choline by a fluorescent cage.
Org Biomol Chem
; 17(21): 5253-5257, 2019 05 29.
Article
de En
| MEDLINE
| ID: mdl-31106320
ABSTRACT
A fluorescent hemicryptophane has been synthesized and can be used as a turn on receptor of acetylcholine. A binding constant of 2.4 × 104 M-1 was measured for this neurotransmitter, and its selective and sensitive detection over choline and choline phosphate was achieved. NMR and DFT calculations provide insight into the interactions involved in this selective recognition process.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Org Biomol Chem
Sujet du journal:
BIOQUIMICA
/
QUIMICA
Année:
2019
Type de document:
Article
Pays d'affiliation:
France