Long-term recurrences of jaw osteoradionecrosis after apparent healing with the PENTOCLO protocol.
J Stomatol Oral Maxillofac Surg
; 121(3): 286-287, 2020 Jun.
Article
de En
| MEDLINE
| ID: mdl-31271892
ABSTRACT
Osteoradionecrosis of the jaws (ORNJ) is a late complication of head and neck irradiation estimated at around 3% of irradiated patients. The PENTO protocol (Pentoxyfilline and Tocopherol), with the eventual adjunction of Clodronate (PENTOCLO), showed interesting results even in advanced ORNJ. The current literature does not describe the long-term outcomes and particularly after the completion of the protocol. The PENTO or PENTOCLO protocol should be prescribed as a life-long treatment or the outcome should be monitored at least as long as the duration of the protocol after its end.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ostéoradionécrose
/
Tumeurs de la tête et du cou
Type d'étude:
Guideline
Limites:
Humans
Langue:
En
Journal:
J Stomatol Oral Maxillofac Surg
Année:
2020
Type de document:
Article
Pays d'affiliation:
France