A Regenerative Endodontic Approach in Mature Ferret Teeth Using Rodent Preameloblast-conditioned Medium.
In Vivo
; 33(4): 1143-1150, 2019.
Article
de En
| MEDLINE
| ID: mdl-31280203
ABSTRACT
BACKGROUND:
This study evaluated the effectiveness of a regenerative endodontic approach to regenerate the pulp tissue in mature teeth of ferret. The presence of odontoblast-like cells in the newly-formed tissue of teeth treated with or without preameloblast-conditioned medium was evaluated based on morphological criteria. MATERIALS ANDMETHODS:
Twenty-four canines from six ferrets were treated. The pulp was removed, and the apical foramen was enlarged. After inducing the formation of a blood clot, a collagen sponge with or without preameloblast-conditioned medium was placed underneath the cementoenamel junction. The samples were analyzed at the eighth week of follow-up.RESULTS:
Vascularized connective tissue was observed in 50% of teeth, without differences between groups. The tissue occupied the apical third of the root canals. Odontoblast-like cells were not observed in any group.CONCLUSION:
Revitalization of mature teeth is possible, at least in the apical third of the root canal. Further experimental research is needed to produce more reliable outcomes.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Milieux de culture conditionnés
/
Organe de l'émail
/
Améloblastes
/
Endodontie régénératrice
/
Odontogenèse
Limites:
Animals
Langue:
En
Journal:
In Vivo
Sujet du journal:
NEOPLASIAS
Année:
2019
Type de document:
Article
Pays d'affiliation:
Espagne