Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial.

Modjarrad, Kayvon; Roberts, Christine C; Mills, Kristin T; Castellano, Amy R; Paolino, Kristopher; Muthumani, Kar; Reuschel, Emma L; Robb, Merlin L; Racine, Trina; Oh, Myoung-Don; Lamarre, Claude; Zaidi, Faraz I; Boyer, Jean; Kudchodkar, Sagar B; Jeong, Moonsup; Darden, Janice M; Park, Young K; Scott, Paul T; Remigio, Celine; Parikh, Ajay P; Wise, Megan C; Patel, Ami; Duperret, Elizabeth K; Kim, Kevin Y; Choi, Hyeree; White, Scott; Bagarazzi, Mark; May, Jeanine M; Kane, Deborah; Lee, Hyojin; Kobinger, Gary; Michael, Nelson L; Weiner, David B; Thomas, Stephen J; Maslow, Joel N

Modjarrad, Kayvon; Roberts, Christine C; Mills, Kristin T; Castellano, Amy R; Paolino, Kristopher; Muthumani, Kar; Reuschel, Emma L; Robb, Merlin L; Racine, Trina; Oh, Myoung-Don; Lamarre, Claude; Zaidi, Faraz I; Boyer, Jean; Kudchodkar, Sagar B; Jeong, Moonsup; Darden, Janice M; Park, Young K; Scott, Paul T; Remigio, Celine; Parikh, Ajay P; Wise, Megan C; Patel, Ami; Duperret, Elizabeth K; Kim, Kevin Y; Choi, Hyeree; White, Scott; Bagarazzi, Mark; May, Jeanine M; Kane, Deborah; Lee, Hyojin; Kobinger, Gary; Michael, Nelson L; Weiner, David B; Thomas, Stephen J; Maslow, Joel N.

Affiliation

Modjarrad K; Walter Reed Army Institute for Research, Silver Spring, MD, USA.
Roberts CC; GeneOne Life Science, Seoul, South Korea. Electronic address: croberts@geneonels-us.com.
Mills KT; ICON Clinical Research Management, Gaithersburg, MD, USA.
Castellano AR; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Paolino K; Walter Reed Army Institute for Research, Silver Spring, MD, USA.
Muthumani K; Wistar Institute, Philadelphia, PA, USA.
Reuschel EL; Wistar Institute, Philadelphia, PA, USA.
Robb ML; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Racine T; Université Laval, Quebec City, QC, Canada.
Oh MD; Seoul National University College of Medicine, Seoul, South Korea.
Lamarre C; Université Laval, Quebec City, QC, Canada.
Zaidi FI; Wistar Institute, Philadelphia, PA, USA.
Boyer J; Inovio Pharmaceuticals, Plymouth Meeting, PA, USA.
Kudchodkar SB; GeneOne Life Science, Seoul, South Korea.
Jeong M; GeneOne Life Science, Seoul, South Korea.
Darden JM; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Park YK; GeneOne Life Science, Seoul, South Korea.
Scott PT; Walter Reed Army Institute for Research, Silver Spring, MD, USA.
Remigio C; GeneOne Life Science, Seoul, South Korea.
Parikh AP; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Wise MC; Inovio Pharmaceuticals, Plymouth Meeting, PA, USA.
Patel A; Wistar Institute, Philadelphia, PA, USA.
Duperret EK; Wistar Institute, Philadelphia, PA, USA.
Kim KY; Wistar Institute, Philadelphia, PA, USA.
Choi H; Wistar Institute, Philadelphia, PA, USA.
White S; Inovio Pharmaceuticals, Plymouth Meeting, PA, USA.
Bagarazzi M; Inovio Pharmaceuticals, Plymouth Meeting, PA, USA.
May JM; Emmes Corporation, Rockville, MD, USA.
Kane D; GeneOne Life Science, Seoul, South Korea.
Lee H; GeneOne Life Science, Seoul, South Korea.
Kobinger G; Université Laval, Quebec City, QC, Canada.
Michael NL; Walter Reed Army Institute for Research, Silver Spring, MD, USA.
Weiner DB; Wistar Institute, Philadelphia, PA, USA.
Thomas SJ; Walter Reed Army Institute for Research, Silver Spring, MD, USA.
Maslow JN; GeneOne Life Science, Seoul, South Korea.

Lancet Infect Dis ; 19(9): 1013-1022, 2019 09.

Article de En | MEDLINE | ID: mdl-31351922

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: ADN viral / Vaccins antiviraux / Anticorps neutralisants / Coronavirus du syndrome respiratoire du Moyen-Orient / Anticorps antiviraux Type d'étude: Guideline Limites: Adult / Female / Humans / Male Langue: En Journal: Lancet Infect Dis Sujet du journal: DOENCAS TRANSMISSIVEIS Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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