Photoinduced synthesis of fluorinated dibenz[b,e]azepines via radical triggered cyclization.
Chem Commun (Camb)
; 55(73): 10848-10851, 2019 Sep 10.
Article
de En
| MEDLINE
| ID: mdl-31417993
ABSTRACT
A simple, mild and efficient approach to access fluorinated dibenz[b,e]azepines via visible-light photoredox catalysis is presented. Inexpensive and commercially available fluoroalkyl anhydrides in concert with pyridine N-oxide are employed as the source of the fluoroalkyl radicals. A one-pot process involving the trifluoroacetylation of unprotected secondary benzyl amines followed by radical cyclization could also afford the desired fluorinated dibenz[b,e]azepines.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Langue:
En
Journal:
Chem Commun (Camb)
Sujet du journal:
QUIMICA
Année:
2019
Type de document:
Article