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Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction.
Qian, Wei; Kumar, Namrata; Roginskaya, Vera; Fouquerel, Elise; Opresko, Patricia L; Shiva, Sruti; Watkins, Simon C; Kolodieznyi, Dmytro; Bruchez, Marcel P; Van Houten, Bennett.
Affiliation
  • Qian W; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Kumar N; University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Roginskaya V; University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Fouquerel E; Molecular Genetics and Developmental Biology Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Opresko PL; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Shiva S; University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Watkins SC; University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Kolodieznyi D; Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261.
  • Bruchez MP; University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.
  • Van Houten B; Department of Environmental and Occupational Health, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA 15261.
Proc Natl Acad Sci U S A ; 116(37): 18435-18444, 2019 09 10.
Article de En | MEDLINE | ID: mdl-31451640

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Télomère / Mitochondries Type d'étude: Etiology_studies Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays de publication: États-Unis d'Amérique

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Télomère / Mitochondries Type d'étude: Etiology_studies Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays de publication: États-Unis d'Amérique