Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.

Guerrero, Erika N; Mitra, Joy; Wang, Haibo; Rangaswamy, Suganya; Hegde, Pavana M; Basu, Priyadarshini; Rao, K S; Hegde, Muralidhar L

Guerrero, Erika N; Mitra, Joy; Wang, Haibo; Rangaswamy, Suganya; Hegde, Pavana M; Basu, Priyadarshini; Rao, K S; Hegde, Muralidhar L.

Affiliation

Guerrero EN; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Mitra J; Center for Neuroscience, Instituto de Investigaciones Científicas y Servicios de Alta Tecnología (INDICASAT AIP), City of Knowledge, Republic of Panama.
Wang H; Department of Biotechnology, Acharya Nagarjuna University, Guntur 522510, India.
Rangaswamy S; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Hegde PM; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Basu P; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Rao KS; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.
Hegde ML; Department of Radiation Oncology, Houston Methodist Research Institute, Houston, TX 77030, USA.

Hum Mol Genet ; 28(18): 3161-3162, 2019 Sep 15.

Article de En | MEDLINE | ID: mdl-31504503

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Type d'étude: Risk_factors_studies Langue: En Journal: Hum Mol Genet Sujet du journal: BIOLOGIA MOLECULAR / GENETICA MEDICA Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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