Leukemic lineage switch in a t(8;22)(p11.2;q11.2)/<i>BCR-FGFR1</i>-rearranged myeloid/lymphoid neoplasm with <i>RUNX1</i> mutation - diagnostic pitfalls and clinical management including FGFR1 inhibitor pemigatinib.

Manur, Rashmi; Sung, Pamela J; Loren, Alison W; Ritchie, Ellen K; Frank, Dale; Bagg, Adam; Geyer, Julia T; Bogusz, Agata M

Leukemic lineage switch in a t(8;22)(p11.2;q11.2)/BCR-FGFR1-rearranged myeloid/lymphoid neoplasm with RUNX1 mutation - diagnostic pitfalls and clinical management including FGFR1 inhibitor pemigatinib.

Manur, Rashmi; Sung, Pamela J; Loren, Alison W; Ritchie, Ellen K; Frank, Dale; Bagg, Adam; Geyer, Julia T; Bogusz, Agata M.

Affiliation

Manur R; Department of Pathology and Laboratory Medicine, Pennsylvania Hospital of the University of Pennsylvania Health System, Philadelphia, PA, USA.
Sung PJ; Department of Medicine, Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Loren AW; Department of Medicine, Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Ritchie EK; Department of Medicine, Leukemia Program, Weill Cornell Medicine, New York, NY, USA.
Frank D; Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Bagg A; Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Geyer JT; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Bogusz AM; Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Leuk Lymphoma ; 61(2): 450-454, 2020 02.

Article de En | MEDLINE | ID: mdl-31524018

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Pyrimidines / Pyrroles / Leucémie myéloïde / Morpholines / Sous-unité alpha 2 du facteur CBF Type d'étude: Diagnostic_studies Limites: Humans / Male / Middle aged Langue: En Journal: Leuk Lymphoma Sujet du journal: HEMATOLOGIA / NEOPLASIAS Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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