A new photosafety screening strategy based on in chemico photoreactivity and in vitro skin exposure for dermally-applied chemicals.

Iyama, Yosuke; Sato, Hideyuki; Seto, Yoshiki; Onoue, Satomi

Iyama, Yosuke; Sato, Hideyuki; Seto, Yoshiki; Onoue, Satomi.

Affiliation

Iyama Y; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Sato H; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Seto Y; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan.
Onoue S; Laboratory of Biopharmacy, School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka, 422-8526, Japan. Electronic address: onoue@u-shizuoka-ken.ac.jp.

Toxicol Lett ; 317: 45-52, 2019 Dec 15.

Article de En | MEDLINE | ID: mdl-31557510

Sujet(s)
Mots clés

In vitro skin permeation test; Photosafety assessment; Phototoxicity; Reactive oxygen species; Skin exposure

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peau / Acridines / Dermatite phototoxique Type d'étude: Diagnostic_studies / Etiology_studies / Screening_studies Limites: Animals Langue: En Journal: Toxicol Lett Année: 2019 Type de document: Article Pays d'affiliation: Japon Pays de publication: Pays-Bas

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