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Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy.
Klimovich, Boris; Mutlu, Samet; Schneikert, Jean; Elmshäuser, Sabrina; Klimovich, Maria; Nist, Andrea; Mernberger, Marco; Timofeev, Oleg; Stiewe, Thorsten.
Affiliation
  • Klimovich B; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Mutlu S; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Schneikert J; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Elmshäuser S; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Klimovich M; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Nist A; Genomics Core Facility, Philipps University Marburg, 35043 Marburg, Germany.
  • Mernberger M; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Timofeev O; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany.
  • Stiewe T; Institute of Molecular Oncology, Member of the German Center for Lung Research, Philipps University Marburg, 35043 Marburg, Germany; stiewe@uni-marburg.de.
Proc Natl Acad Sci U S A ; 116(44): 22288-22293, 2019 10 29.
Article de En | MEDLINE | ID: mdl-31611375
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Thérapie génétique / Protéine p53 suppresseur de tumeur / Carcinogenèse / Lymphomes Limites: Animals / Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Thérapie génétique / Protéine p53 suppresseur de tumeur / Carcinogenèse / Lymphomes Limites: Animals / Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2019 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique