Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

Chevalier, Frédéric D; Le Clec'h, Winka; McDew-White, Marina; Menon, Vinay; Guzman, Meghan A; Holloway, Stephen P; Cao, Xiaohang; Taylor, Alexander B; Kinung'hi, Safari; Gouvras, Anouk N; Webster, Bonnie L; Webster, Joanne P; Emery, Aidan M; Rollinson, David; Garba Djirmay, Amadou; Al Mashikhi, Khalid M; Al Yafae, Salem; Idris, Mohamed A; Moné, Hélène; Mouahid, Gabriel; Hart, P John; LoVerde, Philip T; Anderson, Timothy J C

Chevalier, Frédéric D; Le Clec'h, Winka; McDew-White, Marina; Menon, Vinay; Guzman, Meghan A; Holloway, Stephen P; Cao, Xiaohang; Taylor, Alexander B; Kinung'hi, Safari; Gouvras, Anouk N; Webster, Bonnie L; Webster, Joanne P; Emery, Aidan M; Rollinson, David; Garba Djirmay, Amadou; Al Mashikhi, Khalid M; Al Yafae, Salem; Idris, Mohamed A; Moné, Hélène; Mouahid, Gabriel; Hart, P John; LoVerde, Philip T; Anderson, Timothy J C.

Affiliation

Chevalier FD; Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Le Clec'h W; Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
McDew-White M; Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Menon V; Texas Biomedical Research Institute, San Antonio, Texas, United States of America.
Guzman MA; Departments of Pathology and University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Holloway SP; Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Cao X; Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Taylor AB; Biochemistry & Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Kinung'hi S; X-ray Crystallography Core Laboratory, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America.
Gouvras AN; National Institute for Medical Research, Mwanza, United Republic of Tanzania.
Webster BL; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom.
Webster JP; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom.
Emery AM; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom.
Rollinson D; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom.
Garba Djirmay A; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom.
Al Mashikhi KM; Centre for Emerging, Endemic and Exotic Diseases (CEEED), Royal Veterinary College, University of London, United Kingdom.
Al Yafae S; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom.
Idris MA; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom.
Moné H; London Centre for Neglected Tropical Disease Research (LCNDTR), Imperial Collge, London, United Kingdom.
Mouahid G; Wolfson Wellcome Biomedical Laboratories, Natural History Museum, London, United Kingdom.
Hart PJ; Réseau International Schistosomiases Environnemental Aménagement et Lutte (RISEAL), Niamey, Niger.
LoVerde PT; World Health Organization, Geneva, Switzerland.
Anderson TJC; Directorate General of Health Services, Dhofar Governorate, Salalah, Sultanate of Oman.

PLoS Pathog ; 15(10): e1007881, 2019 10.

Article de En | MEDLINE | ID: mdl-31652296

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oxamniquine / Schistosoma mansoni / Schistosomicides / Résistance aux substances Type d'étude: Prognostic_studies Limites: Animals / Humans Pays/Région comme sujet: Africa / Asia Langue: En Journal: PLoS Pathog Année: 2019 Type de document: Article Pays d'affiliation: États-Unis d'Amérique

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