Active DNA unwinding and transport by a membrane-adapted helicase nanopore.

Sun, Ke; Zhao, Changjian; Zeng, Xiaojun; Chen, Yuejia; Jiang, Xin; Ding, Xianting; Gou, Lu; Xie, Haiyang; Li, Xinqiong; Zhang, Xialin; Lin, Sheng; Dou, Linqin; Wei, Long; Niu, Haofu; Zhang, Ming; Tian, Ruocen; Sawyer, Erica; Yuan, Qingyue; Huang, Yuqin; Chen, Piaopiao; Zhao, Chengjian; Zhou, Cuisong; Ying, Binwu; Shi, Bingyang; Wei, Xiawei; Jiang, Ruotian; Zhang, Lei; Lu, Guangwen; Geng, Jia

Sun, Ke; Zhao, Changjian; Zeng, Xiaojun; Chen, Yuejia; Jiang, Xin; Ding, Xianting; Gou, Lu; Xie, Haiyang; Li, Xinqiong; Zhang, Xialin; Lin, Sheng; Dou, Linqin; Wei, Long; Niu, Haofu; Zhang, Ming; Tian, Ruocen; Sawyer, Erica; Yuan, Qingyue; Huang, Yuqin; Chen, Piaopiao; Zhao, Chengjian; Zhou, Cuisong; Ying, Binwu; Shi, Bingyang; Wei, Xiawei; Jiang, Ruotian; Zhang, Lei; Lu, Guangwen; Geng, Jia.

Affiliation

Sun K; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zhao C; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zeng X; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Chen Y; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Jiang X; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Ding X; Institute for Personalized Medicine, State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Gou L; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China.
Xie H; Institute for Personalized Medicine, State Key Laboratory of Oncogenes and Related Genes, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Li X; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zhang X; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Lin S; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Dou L; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Wei L; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Niu H; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zhang M; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Tian R; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Sawyer E; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Yuan Q; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Huang Y; College of Chemistry, Sichuan University, Chengdu, 610041, China.
Chen P; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zhao C; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Zhou C; College of Chemistry, Sichuan University, Chengdu, 610041, China.
Ying B; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Shi B; Henan-Macquarie Uni Joint Center for Biomedical Innovation, School of Life Sciences, Henan University, Kaifeng, Henan, 475004, China.
Wei X; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China.
Jiang R; Laboratory of Anesthesia and Critical Care Medicine, Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, China.
Zhang L; MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, School of Science, Xi'an Jiaotong University, Xi'an, 710049, China. zhangleio@mail.xjtu.edu.cn.
Lu G; West China Hospital Emergency Department (WCHED), State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. lugw@scu.edu.cn.
Geng J; Department of Laboratory Medicine, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, 610041, China. geng.jia@scu.edu.cn.

Nat Commun ; 10(1): 5083, 2019 11 08.

Article de En | MEDLINE | ID: mdl-31704937

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéines virales / ADN simple brin / Helicase / Protéines de liaison à l'ADN / Nanopores / Double couche lipidique Limites: Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2019 Type de document: Article Pays d'affiliation: Chine

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