Antisense LNA-loaded nanoparticles of star-shaped glucose-core PCL-PEG copolymer for enhanced inhibition of oncomiR-214 and nucleolin-mediated therapy of cisplatin-resistant ovarian cancer cells.

Vandghanooni, Somayeh; Eskandani, Morteza; Barar, Jaleh; Omidi, Yadollah

Vandghanooni, Somayeh; Eskandani, Morteza; Barar, Jaleh; Omidi, Yadollah.

Affiliation

Vandghanooni S; Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Eskandani M; Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Barar J; Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran,; Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Omidi Y; Research Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran,; Department of Pharmaceutics, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. Electronic address: yomidi@tbzmed.ac.ir.

Int J Pharm ; 573: 118729, 2020 Jan 05.

Article de En | MEDLINE | ID: mdl-31705975

Sujet(s)
Mots clés

AS1411 aptamer; Chemoresistant; Chemotherapy; Gene therapy; Locked nucleic acid (LNA) antisense; Ovarian cancer; Polymeric nanoparticles; Targeted delivery; miR-214

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oligonucléotides / Tumeurs de l'ovaire / Cisplatine / MicroARN Limites: Animals / Female / Humans Langue: En Journal: Int J Pharm Année: 2020 Type de document: Article Pays d'affiliation: Iran Pays de publication: Pays-Bas

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