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The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.
Torres-Fernández, Lucia A; Jux, Bettina; Bille, Maximilian; Port, Yasmine; Schneider, Karin; Geyer, Matthias; Mayer, Günter; Kolanus, Waldemar.
Affiliation
  • Torres-Fernández LA; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Jux B; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Bille M; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Port Y; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Schneider K; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
  • Geyer M; Institute of Structural Biology, University Clinics Bonn, University of Bonn, 53127 Bonn, Germany.
  • Mayer G; Center of Aptamer Research & Development; Chemical Biology & Chemical Genetics, Life & Medical Sciences Institute (LIMES). University of Bonn, 53121 Bonn, Germany.
  • Kolanus W; Molecular Immunology and Cell Biology, Life & Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany.
Nucleic Acids Res ; 47(22): 11861-11879, 2019 12 16.
Article de En | MEDLINE | ID: mdl-31732746

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Stabilité de l'ARN / Ubiquitin-protein ligases / Inhibiteur p21 de kinase cycline-dépendante / Dégradation des ARNm non-sens / Protéines à motif tripartite Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Nucleic Acids Res Année: 2019 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Stabilité de l'ARN / Ubiquitin-protein ligases / Inhibiteur p21 de kinase cycline-dépendante / Dégradation des ARNm non-sens / Protéines à motif tripartite Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Nucleic Acids Res Année: 2019 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: Royaume-Uni