The Emergence of Successful Streptococcus pyogenes Lineages through Convergent Pathways of Capsule Loss and Recombination Directing High Toxin Expression.

Turner, Claire E; Holden, Matthew T G; Blane, Beth; Horner, Carolyne; Peacock, Sharon J; Sriskandan, Shiranee

Turner, Claire E; Holden, Matthew T G; Blane, Beth; Horner, Carolyne; Peacock, Sharon J; Sriskandan, Shiranee.

Affiliation

Turner CE; Molecular Biology & Biotechnology, The Florey Institute, University of Sheffield, Sheffield, United Kingdom c.e.turner@sheffield.ac.uk.
Holden MTG; Department of Infectious Disease, Imperial College London, London, United Kingdom.
Blane B; Pathogen Genomics, The Wellcome Trust Sanger Institute, Cambridge, United Kingdom.
Horner C; School of Medicine, University of St Andrews, St Andrews, United Kingdom.
Peacock SJ; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.
Sriskandan S; British Society for Antimicrobial Chemotherapy, Birmingham, United Kingdom.

mBio ; 10(6)2019 12 10.

Article de En | MEDLINE | ID: mdl-31822586

Sujet(s)
Mots clés

NADase; Streptococcus pyogenes; convergent evolution; group A Streptococcus; homologous recombination; hyaluronic acid capsule; streptolysin O; whole-genome sequencing

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Infections à streptocoques / Streptococcus pyogenes / Toxines biologiques / Capsules bactériennes / Facteurs de virulence Type d'étude: Prognostic_studies Limites: Humans Pays/Région comme sujet: Europa Langue: En Journal: MBio Année: 2019 Type de document: Article Pays d'affiliation: Royaume-Uni

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