Generation of two NAGLU-mutated homozygous cell lines from healthy induced pluripotent stem cells using CRISPR/Cas9 to model Sanfilippo B syndrome.

Benetó, Noelia; Cozar, Monica; Gort, Laura; Pacheco, Laura; Vilageliu, Lluïsa; Grinberg, Daniel; Canals, Isaac

Benetó, Noelia; Cozar, Monica; Gort, Laura; Pacheco, Laura; Vilageliu, Lluïsa; Grinberg, Daniel; Canals, Isaac.

Affiliation

Benetó N; Department of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, Spain.
Cozar M; Department of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, Spain.
Gort L; Secció d'Errors Congènits del Metabolisme -IBC, Servei de Bioquímica i Genètica Molecular, Hospital Clínic, IDIBAPS, CIBERER, Barcelona, Spain.
Pacheco L; Secció d'Errors Congènits del Metabolisme -IBC, Servei de Bioquímica i Genètica Molecular, Hospital Clínic, IDIBAPS, CIBERER, Barcelona, Spain.
Vilageliu L; Department of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, Spain.
Grinberg D; Department of Genetics, Microbiology and Statistics, Fac. Biology, University of Barcelona, CIBERER, IBUB, IRSJD, Spain.
Canals I; Stem Cells, Aging and Neurodegeneration Group, Lund Stem Cell Center, University Hospital, Lund, Sweden.

Stem Cell Res ; 42: 101668, 2020 01.

Article de En | MEDLINE | ID: mdl-31825816

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Mucopolysaccharidose de type III / Cellules souches pluripotentes induites / Systèmes CRISPR-Cas Limites: Humans Langue: En Journal: Stem Cell Res Année: 2020 Type de document: Article Pays d'affiliation: Espagne

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