Developments in drug design strategies for bromodomain protein inhibitors to target <i>Plasmodium falciparum</i> parasites.

Nguyen, Hanh H T; Yeoh, Lee M; Chisholm, Scott A; Duffy, Michael F

Developments in drug design strategies for bromodomain protein inhibitors to target Plasmodium falciparum parasites.

Nguyen, Hanh H T; Yeoh, Lee M; Chisholm, Scott A; Duffy, Michael F.

Affiliation

Nguyen HHT; The School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia.
Yeoh LM; The Dept of Medicine and Radiology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.
Chisholm SA; The School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia.
Duffy MF; The School of BioSciences, Bio21 Institute, The University of Melbourne, Melbourne, Australia.

Expert Opin Drug Discov ; 15(4): 415-425, 2020 04.

Article de En | MEDLINE | ID: mdl-31870185

Sujet(s)
Mots clés

Acetylation; Apicomplexa; Plasmodium falciparum; bromodomain; epigenetics; histones; malaria; target-based drug discovery

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Plasmodium falciparum / Paludisme à Plasmodium falciparum / Antipaludiques Type d'étude: Prognostic_studies Limites: Animals / Humans Langue: En Journal: Expert Opin Drug Discov Année: 2020 Type de document: Article Pays d'affiliation: Australie

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