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Novel glucagon- and OXM-based peptides acting through glucagon and GLP-1 receptors with body weight reduction and anti-diabetic properties.
Cai, Xingguang; Li, Chengye; Zhou, Jie; Dai, Yuxuan; Avraham, Yosefa; Sun, Lidan; Liu, Chunxia; Tong, Jiayi; Wang, Yao; Bi, Xinzhou; He, Liang; Huang, Wenlong; Qian, Hai.
Affiliation
  • Cai X; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Li C; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Zhou J; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Dai Y; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Avraham Y; Department of Human Nutrition and Metabolism, Braun School of Public Health, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
  • Sun L; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Liu C; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Tong J; Zhongda Hospital, Southeast University, Nanjing 210009, PR China.
  • Wang Y; Zhongda Hospital, Southeast University, Nanjing 210009, PR China.
  • Bi X; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • He L; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Huang W; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China.
  • Qian H; Center of Drug Discovery, State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China; Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China. Electronic addr
Bioorg Chem ; 95: 103538, 2020 01.
Article de En | MEDLINE | ID: mdl-31901754
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides / Glucagon / Perte de poids / Diabète expérimental / Oxyntomoduline / Récepteur du peptide-1 similaire au glucagon / Hypoglycémiants Type d'étude: Etiology_studies Limites: Animals Langue: En Journal: Bioorg Chem Année: 2020 Type de document: Article Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Peptides / Glucagon / Perte de poids / Diabète expérimental / Oxyntomoduline / Récepteur du peptide-1 similaire au glucagon / Hypoglycémiants Type d'étude: Etiology_studies Limites: Animals Langue: En Journal: Bioorg Chem Année: 2020 Type de document: Article Pays de publication: États-Unis d'Amérique