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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Shah, Sonia; Henry, Albert; Roselli, Carolina; Lin, Honghuang; Sveinbjörnsson, Garðar; Fatemifar, Ghazaleh; Hedman, Åsa K; Wilk, Jemma B; Morley, Michael P; Chaffin, Mark D; Helgadottir, Anna; Verweij, Niek; Dehghan, Abbas; Almgren, Peter; Andersson, Charlotte; Aragam, Krishna G; Ärnlöv, Johan; Backman, Joshua D; Biggs, Mary L; Bloom, Heather L; Brandimarto, Jeffrey; Brown, Michael R; Buckbinder, Leonard; Carey, David J; Chasman, Daniel I; Chen, Xing; Chen, Xu; Chung, Jonathan; Chutkow, William; Cook, James P; Delgado, Graciela E; Denaxas, Spiros; Doney, Alexander S; Dörr, Marcus; Dudley, Samuel C; Dunn, Michael E; Engström, Gunnar; Esko, Tõnu; Felix, Stephan B; Finan, Chris; Ford, Ian; Ghanbari, Mohsen; Ghasemi, Sahar; Giedraitis, Vilmantas; Giulianini, Franco; Gottdiener, John S; Gross, Stefan; Guðbjartsson, Daníel F; Gutmann, Rebecca; Haggerty, Christopher M.
Affiliation
  • Shah S; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, 4072, Australia.
  • Henry A; Institute of Cardiovascular Science, University College London, London, UK.
  • Roselli C; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Lin H; Institute of Cardiovascular Science, University College London, London, UK.
  • Sveinbjörnsson G; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Fatemifar G; Institute of Health Informatics, University College London, London, UK.
  • Hedman ÅK; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Wilk JB; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Morley MP; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
  • Chaffin MD; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.
  • Helgadottir A; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.
  • Verweij N; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Dehghan A; Institute of Health Informatics, University College London, London, UK.
  • Almgren P; Health Data Research UK London, University College London, London, UK.
  • Andersson C; Cardiovascular Medicine unit, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden.
  • Aragam KG; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.
  • Ärnlöv J; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Backman JD; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Biggs ML; deCODE genetics/Amgen Inc., Sturlugata 8, 101, Reykjavik, Iceland.
  • Bloom HL; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Brandimarto J; Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
  • Brown MR; Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK.
  • Buckbinder L; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, Imperial College London, St Mary's Campus, London, W2 1PG, UK.
  • Carey DJ; Department of Clinical Sciences, Lund University, Malmö, Sweden.
  • Chasman DI; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study, Framingham, MA, USA.
  • Chen X; Department of Cardiology, Herlev Gentofte Hospital, Herlev Ringvej 57, 2650, Herlev, Denmark.
  • Chen X; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Chung J; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
  • Chutkow W; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
  • Cook JP; Department of Neurobiology, Care Sciences and Society/ Section of Family Medicine and Primary Care, Karolinska Institutet, Stockholm, Sweden.
  • Delgado GE; School of Health and Social Sciences, Dalarna University, Falun, Sweden.
  • Denaxas S; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Doney AS; Department of Biostatistics, University of Washington, Seattle, WA, USA.
  • Dörr M; Department of Medicine, University of Washington, Seattle, WA, USA.
  • Dudley SC; Division of Cardiology, Department of Medicine, Emory University Medical Center, Atlanta, GA, USA.
  • Dunn ME; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Engström G; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, Texas, USA.
  • Esko T; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.
  • Felix SB; Department of Molecular and Functional Genomics, Geisinger, Danville, PA, USA.
  • Finan C; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, 02215, USA.
  • Ford I; Harvard Medical School, Boston, MA, 02115, USA.
  • Ghanbari M; Pfizer Worldwide Research & Development, 1 Portland St, Cambridge, MA, USA.
  • Ghasemi S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Giedraitis V; Regeneron Genetics Center, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
  • Giulianini F; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Gottdiener JS; Department of Biostatistics, University of Liverpool, Liverpool, UK.
  • Gross S; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Heidelberg, Germany.
  • Guðbjartsson DF; British Heart Foundation Research Accelerator, University College London, London, UK.
  • Gutmann R; Institute of Health Informatics, University College London, London, UK.
  • Haggerty CM; Health Data Research UK London, University College London, London, UK.
Nat Commun ; 11(1): 163, 2020 01 09.
Article de En | MEDLINE | ID: mdl-31919418
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Fibrillation auriculaire / Maladie des artères coronaires / Fonction ventriculaire gauche / Défaillance cardiaque / Cardiomyopathies Type d'étude: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limites: Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2020 Type de document: Article Pays d'affiliation: Australie
Texte intégral
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Imprimer
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Fibrillation auriculaire / Maladie des artères coronaires / Fonction ventriculaire gauche / Défaillance cardiaque / Cardiomyopathies Type d'étude: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limites: Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2020 Type de document: Article Pays d'affiliation: Australie