Supraglottic laryngeal sarcoidosis masquerading as supraglottitis.
BMJ Case Rep
; 13(1)2020 Jan 13.
Article
de En
| MEDLINE
| ID: mdl-31937627
ABSTRACT
Sarcoidosis is a rare multisystem disorder of unknown aetiology characterised by non-caseating granulomas in involved organs; it is a diagnosis of exclusion. Laryngeal involvement affects only 0.5%-5% of those with sarcoidosis. It is an uncommon but important cause of supraglottic inflammation and oedema and should be considered in the differential diagnosis in patients with supraglottitis. This case describes a 30-year-old man who presented with stridor and shortness of breath. Flexible nasendoscopic examination revealed a grossly oedematous, pale pink, diffusely hypertrophied epiglottis. Surgical biopsy revealed non-caseating granulomatous inflammation. In the context of exclusion of hepatitis, anti-neutrophil cytoplasmic antibody (ANCA) positivity, malignancy and mycobacterial infection, the diagnosis of supraglottic laryngeal sarcoid was made. He is being treated with azathioprine immunosuppression with symptomatic improvement.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Sarcoïdose
/
Azathioprine
/
Maladies du larynx
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
Limites:
Adult
/
Humans
/
Male
Langue:
En
Journal:
BMJ Case Rep
Année:
2020
Type de document:
Article
Pays d'affiliation:
Australie