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Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Michler, Thomas; Kosinska, Anna D; Festag, Julia; Bunse, Till; Su, Jinpeng; Ringelhan, Marc; Imhof, Hortenzia; Grimm, Dirk; Steiger, Katja; Mogler, Carolin; Heikenwalder, Mathias; Michel, Marie-Louise; Guzman, Carlos A; Milstein, Stuart; Sepp-Lorenzino, Laura; Knolle, Percy; Protzer, Ulrike.
Affiliation
  • Michler T; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany; German Center for Infection Research, Münich, Heidelberg, Germany.
  • Kosinska AD; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany; German Center for Infection Research, Münich, Heidelberg, Germany.
  • Festag J; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany.
  • Bunse T; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany; German Center for Infection Research, Münich, Heidelberg, Germany.
  • Su J; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany.
  • Ringelhan M; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany; Department of Internal Medicine II, University Hospital rechts der Isar, Technical University of Munich, Münich, Germany.
  • Imhof H; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany.
  • Grimm D; German Center for Infection Research, Münich, Heidelberg, Germany; Department of Infectious Diseases/Virology, Heidelberg University Hospital, BioQuant, Heidelberg, Germany.
  • Steiger K; Institute of Pathology, Technical University of Munich, Münich, Germany.
  • Mogler C; Institute of Pathology, Technical University of Munich, Münich, Germany.
  • Heikenwalder M; Division of Chronic Inflammation and Cancer, German Cancer Research Center, Heidelberg, Germany.
  • Michel ML; Institut Pasteur, Paris, France.
  • Guzman CA; German Center for Infection Research, Münich, Heidelberg, Germany; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Milstein S; Alnylam Pharmaceuticals, Cambridge, Massachusetts.
  • Sepp-Lorenzino L; Alnylam Pharmaceuticals, Cambridge, Massachusetts.
  • Knolle P; German Center for Infection Research, Münich, Heidelberg, Germany; Institute of Molecular Immunology, University Hospital rechts der Isar, Technical University of Munich, Münich, Germany.
  • Protzer U; Institute of Virology, Technical University of Münich, Helmholtz Zentrum München, Münich, Germany; German Center for Infection Research, Münich, Heidelberg, Germany. Electronic address: protzer@tum.de.
Gastroenterology ; 158(6): 1762-1775.e9, 2020 05.
Article de En | MEDLINE | ID: mdl-32001321
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Virus de l'hépatite B / Vaccins anti-hépatite B / Hépatite B chronique / Petit ARN interférent / Antigènes de surface du virus de l'hépatite B Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Animals / Female / Humans / Male Langue: En Journal: Gastroenterology Année: 2020 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Virus de l'hépatite B / Vaccins anti-hépatite B / Hépatite B chronique / Petit ARN interférent / Antigènes de surface du virus de l'hépatite B Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Animals / Female / Humans / Male Langue: En Journal: Gastroenterology Année: 2020 Type de document: Article Pays d'affiliation: Allemagne Pays de publication: États-Unis d'Amérique