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An ultrasound-based referential of body height-adjusted normal liver organometry in school children from Bokito in rural Cameroon.
Kamdem, Severin Donald; Kuemkon, Erve Martial; Kamguia, Leonel Meyo; Tchanana, Gladys K; Konhawa, Francis; Nche, Frungwa; Oumarou, Alim; Hamza, Mamadou; Essomba, René Ghislain; Kengne, Michel; Ondigui, Bienvenu Etogo; Assoumou, Marie Claire Okomo; Brombacher, Frank; Nono, Justin Komguep.
Affiliation
  • Kamdem SD; Division of Immunology, Health Science Faculty, University of Cape Town, Cape Town, South Africa.
  • Kuemkon EM; Cape Town Component, International Centre for Genetic Engineering and Biotechnology, Cape Town, South Africa.
  • Kamguia LM; Immunology of Infectious Diseases Unit, South African Medical Research Centre, Cape Town, South Africa.
  • Tchanana GK; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
  • Konhawa F; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
  • Nche F; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
  • Oumarou A; CIAB EXACT Medical Laboratory, Yaoundé, Cameroon.
  • Hamza M; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
  • Essomba RG; Faculty of medicine and biomedical sciences, University of Yaoundé 1, Yaoundé, Cameroon.
  • Kengne M; Ministry of Public health, Yaoundé, Cameroon.
  • Ondigui BE; Ministry of Public health, Yaoundé, Cameroon.
  • Assoumou MCO; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
  • Brombacher F; National Public Health Laboratory, Ministry of Public Health, Yaoundé, Cameroon.
  • Nono JK; School of Health Sciences, Catholic University of Central Africa, Yaoundé, Cameroon.
Sci Rep ; 10(1): 2773, 2020 02 17.
Article de En | MEDLINE | ID: mdl-32066761
The grading system for ultrasonographic assessment of Schistosoma mansoni morbidity is crucial for evaluation of control programs. This requires prior definition of normal liver organometric ranges in the population from the endemic area. A cross-sectional study was conducted in a S. mansoni endemic area in rural Cameroon. 1002 Participants were screened and 234 of them, free from all common liver-affecting diseases in the area (schistosomiasis, malaria, hepatitis B and C) and with no ultrasonographic signs of liver disease were selected and their liver parameters measured by ultrasonography. All statistics were considered significant for p-values < 0.05. Normal dimensions of livers lobe sizes, portal vein wall thickness and portal vein diameters are reported. The liver organometric data are presented for the entire study population as a whole and separately for males and females as prediction plots, with observed values and fitted regression line with 95% confidence. Reference ranges for liver parameters (size, portal vein thickness and diameter) adjusted for body height established in the current study are novel for Cameroon. The prediction plots generated should improve the accuracy of the assessment of liver morbidity by ultrasonography in the region.
Sujet(s)

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Veine porte / Échographie / Foie Type d'étude: Diagnostic_studies / Observational_studies / Risk_factors_studies Limites: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Pays/Région comme sujet: Africa Langue: En Journal: Sci Rep Année: 2020 Type de document: Article Pays d'affiliation: République d'Afrique du Sud Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Veine porte / Échographie / Foie Type d'étude: Diagnostic_studies / Observational_studies / Risk_factors_studies Limites: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Pays/Région comme sujet: Africa Langue: En Journal: Sci Rep Année: 2020 Type de document: Article Pays d'affiliation: République d'Afrique du Sud Pays de publication: Royaume-Uni