Different baseline characteristics are associated with incident wheeze in female and male adolescents.
Acta Paediatr
; 109(11): 2324-2331, 2020 11.
Article
de En
| MEDLINE
| ID: mdl-32187749
ABSTRACT
AIM:
To investigate the independent relationships between baseline characteristics and incident wheeze in adolescents, with particular regard to gender.METHODS:
Adolescents (N = 959), aged 12-15 years, answered a standardised respiratory questionnaire and underwent height and weight measurements at baseline. Four years later, 96% of the subjects completed a similar questionnaire. The present study included the adolescents without self-reported wheeze at baseline (n = 795; 394 girls).RESULTS:
The proportion of adolescents with obesity was higher among subjects with incident wheeze than among subjects who never reported wheeze 19.1% vs 8.3%. When stratifying for gender, this difference was only found in girls. In stepwise logistic regression models (odds ratios [95% confidence interval]), obesity (2.84 [1.17-6.86]) and rhinitis (3.04 [1.53-6.03]) at baseline and current smoking (2.60 [1.16-5.82]) at follow-up were associated with incident wheeze in girls. For boys, FEV1 <-1.65 standard deviation (3.20 [1.04-9.79]), family asthma (3.16 [1.46-6.86]) and seasonal allergic symptoms (5.61 [2.56-12.27]) at baseline were independently associated with incident wheeze.CONCLUSION:
Data stratified by gender showed that obesity in girls and an atopic constitution in boys were independently associated with increased risk of developing wheeze within four years.Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Asthme
/
Rhinite
Type d'étude:
Etiology_studies
/
Prevalence_studies
/
Prognostic_studies
Limites:
Adolescent
/
Child
/
Female
/
Humans
/
Male
Langue:
En
Journal:
Acta Paediatr
Année:
2020
Type de document:
Article
Pays d'affiliation:
Suède