Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types.

Ravindra Kumar, Sripriya; Miles, Timothy F; Chen, Xinhong; Brown, David; Dobreva, Tatyana; Huang, Qin; Ding, Xiaozhe; Luo, Yicheng; Einarsson, Pétur H; Greenbaum, Alon; Jang, Min J; Deverman, Benjamin E; Gradinaru, Viviana

Ravindra Kumar, Sripriya; Miles, Timothy F; Chen, Xinhong; Brown, David; Dobreva, Tatyana; Huang, Qin; Ding, Xiaozhe; Luo, Yicheng; Einarsson, Pétur H; Greenbaum, Alon; Jang, Min J; Deverman, Benjamin E; Gradinaru, Viviana.

Affiliation

Ravindra Kumar S; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Miles TF; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Chen X; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Brown D; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Dobreva T; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Huang Q; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Ding X; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA.
Luo Y; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Einarsson PH; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Greenbaum A; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Jang MJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.
Deverman BE; Joint Department of Biomedical Engineering, North Carolina State University, Raleigh, NC, USA.
Gradinaru V; University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Nat Methods ; 17(5): 541-550, 2020 05.

Article de En | MEDLINE | ID: mdl-32313222

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Encéphale / Génie génétique / Techniques de transfert de gènes / Dependovirus / Integrases / Protéines de capside / Vecteurs génétiques Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: Nat Methods Sujet du journal: TECNICAS E PROCEDIMENTOS DE LABORATORIO Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: États-Unis d'Amérique

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