N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma.

Tjaden, Britta; Baum, Katharina; Marquardt, Viktoria; Simon, Mareike; Trajkovic-Arsic, Marija; Kouril, Theresa; Siebers, Bettina; Lisec, Jan; Siveke, Jens T; Schulte, Johannes H; Benary, Uwe; Remke, Marc; Wolf, Jana; Schramm, Alexander

Tjaden, Britta; Baum, Katharina; Marquardt, Viktoria; Simon, Mareike; Trajkovic-Arsic, Marija; Kouril, Theresa; Siebers, Bettina; Lisec, Jan; Siveke, Jens T; Schulte, Johannes H; Benary, Uwe; Remke, Marc; Wolf, Jana; Schramm, Alexander.

Affiliation

Tjaden B; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Baum K; Mathematical Modeling of Cellular Processes, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Marquardt V; Division of Pediatric Neuro-Oncogenomics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Partner Site Essen / Düsseldorf; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf; Department of Neuropathology, Me
Simon M; Mathematical Modeling of Cellular Processes, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Trajkovic-Arsic M; Division of Solid Tumor Translational Oncology, West German Cancer Center, Cniversity Hospital Essen, Essen, Germany and German Cancer Consortium (DKTK, partner site Essen), Essen, Germany.
Kouril T; Molecular Enzyme Technology and Biochemistry (MEB), Biofilm Centre, Faculty of Chemistry, University of Duisburg-Essen, Duisburg, Germany.
Siebers B; Molecular Enzyme Technology and Biochemistry (MEB), Biofilm Centre, Faculty of Chemistry, University of Duisburg-Essen, Duisburg, Germany.
Lisec J; Federal Institute for Materials Research and Testing (BAM), Analytical Chemistry, Berlin, Germany.
Siveke JT; Division of Solid Tumor Translational Oncology, West German Cancer Center, Cniversity Hospital Essen, Essen, Germany and German Cancer Consortium (DKTK, partner site Essen), Essen, Germany.
Schulte JH; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin; Berlin Institute of Health (BIH), Berlin, Germany; Department of Pediatric Hematology/Oncology/Stem Cell Transplantation, Berlin, Germany; German Cancer Consortium (DKTK), Heidelberg,
Benary U; Mathematical Modeling of Cellular Processes, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Remke M; Division of Pediatric Neuro-Oncogenomics, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Partner Site Essen / Düsseldorf; Department of Pediatric Oncology, Hematology and Clinical Immunology, Medical Faculty, University Hospital Düsseldorf; Department of Neuropathology, Me
Wolf J; Mathematical Modeling of Cellular Processes, Max-Delbrück-Center for Molecular Medicine, Berlin, Germany.
Schramm A; Department of Medical Oncology, West German Cancer Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany. alexander.schramm@uk-essen.de.

Sci Rep ; 10(1): 7157, 2020 04 28.

Article de En | MEDLINE | ID: mdl-32346009

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Protéine du proto-oncogène N-Myc / Neuroblastome Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: Sci Rep Année: 2020 Type de document: Article Pays d'affiliation: Allemagne

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