Idebenone Has Distinct Effects on Mitochondrial Respiration in Cortical Astrocytes Compared to Cortical Neurons Due to Differential NQO1 Activity.

Jaber, Sausan M; Ge, Shealinna X; Milstein, Joshua L; VanRyzin, Jonathan W; Waddell, Jaylyn; Polster, Brian M

Jaber, Sausan M; Ge, Shealinna X; Milstein, Joshua L; VanRyzin, Jonathan W; Waddell, Jaylyn; Polster, Brian M.

Affiliation

Jaber SM; Department of Anesthesiology and Center for Shock, Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Ge SX; Department of Biochemistry and Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Milstein JL; Department of Anesthesiology and Center for Shock, Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, Maryland 21201.
VanRyzin JW; Department of Anesthesiology and Center for Shock, Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Waddell J; Program in Neuroscience, University of Maryland School of Medicine, Baltimore, Maryland 21201.
Polster BM; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, Maryland 21201.

J Neurosci ; 40(23): 4609-4619, 2020 06 03.

Article de En | MEDLINE | ID: mdl-32350039

Sujet(s)
Mots clés

Catena; Complex I; LHON; Nrf2; Raxone; carnosic acid

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Astrocytes / Ubiquinones / NADPH dehydrogenase (quinone) / Respiration cellulaire / Mitochondries / Antioxydants Type d'étude: Prognostic_studies Limites: Animals Langue: En Journal: J Neurosci Année: 2020 Type de document: Article Pays de publication: États-Unis d'Amérique

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