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Signal profiling of the ß1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by ß1AR and ß2AR.
Lukasheva, Viktoriya; Devost, Dominic; Le Gouill, Christian; Namkung, Yoon; Martin, Ryan D; Longpré, Jean-Michel; Amraei, Mohammad; Shinjo, Yuji; Hogue, Mireille; Lagacé, Monique; Breton, Billy; Aoki, Junken; Tanny, Jason C; Laporte, Stéphane A; Pineyro, Graciela; Inoue, Asuka; Bouvier, Michel; Hébert, Terence E.
Affiliation
  • Lukasheva V; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada.
  • Devost D; Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.
  • Le Gouill C; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada.
  • Namkung Y; Department of Medicine, Research Institute of the McGill University Health Centre, McGill University, Montréal, Québec, Canada.
  • Martin RD; Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.
  • Longpré JM; Institut de Pharmacologie and Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Canada.
  • Amraei M; Department of Pharmacology and Physiology, Université de Montréal, Centre de Recherche de l'Hôpital Ste-Justine, Montréal, Canada.
  • Shinjo Y; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Hogue M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada.
  • Lagacé M; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada.
  • Breton B; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada.
  • Aoki J; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Tanny JC; Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.
  • Laporte SA; Department of Pharmacology and Therapeutics, McGill University, Montréal, Québec, Canada.
  • Pineyro G; Department of Medicine, Research Institute of the McGill University Health Centre, McGill University, Montréal, Québec, Canada.
  • Inoue A; Department of Pharmacology and Physiology, Université de Montréal, Centre de Recherche de l'Hôpital Ste-Justine, Montréal, Canada.
  • Bouvier M; Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan.
  • Hébert TE; Department of Biochemistry and Molecular Medicine, Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montréal, Québec, Canada. michel.bouvier@umontreal.ca.
Sci Rep ; 10(1): 8779, 2020 05 29.
Article de En | MEDLINE | ID: mdl-32471984
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs bêta-2 adrénergiques / Récepteurs bêta-1 adrénergiques / Sous-unités alpha Gs des protéines G / Sous-unités alpha G12-G13 des protéines G Limites: Humans Langue: En Journal: Sci Rep Année: 2020 Type de document: Article Pays d'affiliation: Canada
Texte intégral
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Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteurs bêta-2 adrénergiques / Récepteurs bêta-1 adrénergiques / Sous-unités alpha Gs des protéines G / Sous-unités alpha G12-G13 des protéines G Limites: Humans Langue: En Journal: Sci Rep Année: 2020 Type de document: Article Pays d'affiliation: Canada