MYC protein stability is negatively regulated by BRD4.

Devaiah, Ballachanda N; Mu, Jie; Akman, Ben; Uppal, Sheetal; Weissman, Jocelyn D; Cheng, Dan; Baranello, Laura; Nie, Zuqin; Levens, David; Singer, Dinah S

Devaiah, Ballachanda N; Mu, Jie; Akman, Ben; Uppal, Sheetal; Weissman, Jocelyn D; Cheng, Dan; Baranello, Laura; Nie, Zuqin; Levens, David; Singer, Dinah S.

Affiliation

Devaiah BN; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Mu J; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Akman B; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Uppal S; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Weissman JD; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Cheng D; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892.
Baranello L; Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD 20892.
Nie Z; Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD 20892.
Levens D; Laboratory of Pathology, National Cancer Institute, NIH, Bethesda, MD 20892.
Singer DS; Experimental Immunology Branch, National Cancer Institute, NIH, Bethesda, MD 20892; dinah.singer@nih.gov.

Proc Natl Acad Sci U S A ; 117(24): 13457-13467, 2020 06 16.

Article de En | MEDLINE | ID: mdl-32482868

Sujet(s)
Mots clés

BRD4 histone acetyltransferase; BRD4 kinase; ERK1; MYC phosphorylation; MYC stability

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Facteurs de transcription / Protéines proto-oncogènes c-myc / Protéines du cycle cellulaire Limites: Humans Langue: En Journal: Proc Natl Acad Sci U S A Année: 2020 Type de document: Article

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