The soluble sperm factor that activates the egg: PLCzeta and beyond.
Reproduction
; 160(1): V9-V11, 2020 07.
Article
de En
| MEDLINE
| ID: mdl-32485666
ABSTRACT
PLCzeta(ζ) initiates Ca2+ oscillations and egg activation at fertilization in mammals, but studies in mouse eggs fertilized by PLCζ knockout (KO) sperm imply that there is another slow acting factor causing Ca2+ release. Here, I propose a hypothesis for how this second sperm factor might cause Ca2+ oscillations in mouse eggs.
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Ovule
/
Spermatozoïdes
/
Calcium
/
Signalisation calcique
/
Phosphoinositide Phospholipase C
/
Fécondation
Limites:
Animals
Langue:
En
Journal:
Reproduction
Sujet du journal:
MEDICINA REPRODUTIVA
Année:
2020
Type de document:
Article
Pays d'affiliation:
Royaume-Uni