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Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor.
Tamir, Tigist Y; Bowman, Brittany M; Agajanian, Megan J; Goldfarb, Dennis; Schrank, Travis P; Stohrer, Trent; Hale, Andrew E; Siesser, Priscila F; Weir, Seth J; Murphy, Ryan M; LaPak, Kyle M; Weissman, Bernard E; Moorman, Nathaniel J; Major, M Ben.
Affiliation
  • Tamir TY; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Bowman BM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Agajanian MJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Goldfarb D; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Schrank TP; Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Stohrer T; Institute for Informatics, School of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA.
  • Hale AE; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Siesser PF; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Weir SJ; Department of Computer Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Murphy RM; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA.
  • LaPak KM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Weissman BE; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Moorman NJ; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Major MB; Department of Cell Biology and Physiology, Washington University in St. Louis, St. Louis, MO 63110, USA.
J Cell Sci ; 133(14)2020 07 15.
Article de En | MEDLINE | ID: mdl-32546533

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur EphA5 / Facteur-2 apparenté à NF-E2 Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: J Cell Sci Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Récepteur EphA5 / Facteur-2 apparenté à NF-E2 Type d'étude: Prognostic_studies Limites: Humans Langue: En Journal: J Cell Sci Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni