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Segmentation of small ground glass opacity pulmonary nodules based on Markov random field energy and Bayesian probability difference.
Zhang, Shaorong; Chen, Xiangmeng; Zhu, Zhibin; Feng, Bao; Chen, Yehang; Long, Wansheng.
Affiliation
  • Zhang S; School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin, 541004, China.
  • Chen X; School of Electronic Information and Automation, Guilin University of Aerospace Technology, Guilin, 541004, China.
  • Zhu Z; The Department of Radiology, The Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529000, China.
  • Feng B; School of Mathematics and Computational Science, Guilin University of Electronic Technology, Guilin, 541004, China. optimization_zhu@163.com.
  • Chen Y; School of Electronic Information and Automation, Guilin University of Aerospace Technology, Guilin, 541004, China.
  • Long W; The Department of Radiology, The Affiliated Jiangmen Hospital of Sun Yat-sen University, Jiangmen, 529000, China.
Biomed Eng Online ; 19(1): 51, 2020 Jun 17.
Article de En | MEDLINE | ID: mdl-32552724
BACKGROUND: Image segmentation is an important part of computer-aided diagnosis (CAD), the segmentation of small ground glass opacity (GGO) pulmonary nodules is beneficial for the early detection of lung cancer. For the segmentation of small GGO pulmonary nodules, an integrated active contour model based on Markov random field energy and Bayesian probability difference (IACM_MRFEBPD) is proposed in this paper. METHODS: First, the Markov random field (MRF) is constructed on the computed tomography (CT) images, then the MRF energy is calculated. The MRF energy is used to construct the region term. It can not only enhance the contrast between pulmonary nodule and the background region, but also solve the problem of intensity inhomogeneity using local spatial correlation information between neighboring pixels in the image. Second, the Gaussian mixture model is used to establish the probability model of the image, and the model parameters are estimated by the expectation maximization (EM) algorithm. So the Bayesian posterior probability difference of each pixel can be calculated. The probability difference is used to construct the boundary detection term, which is 0 at the boundary. Therefore, the blurred boundary problem can be solved. Finally, under the framework of the level set, the integrated active contour model is constructed. RESULTS: To verify the effectiveness of the proposed method, the public data of the lung image database consortium and image database resource initiative (LIDC-IDRI) and the clinical data of the Affiliated Jiangmen Hospital of Sun Yat-sen University are used to perform experiments, and the intersection over union (IOU) score is used to evaluate the segmentation methods. Compared with other methods, the proposed method achieves the best results with the highest average IOU of 0.7444, 0.7503, and 0.7450 for LIDC-IDRI test set, clinical test set, and all test sets, respectively. CONCLUSIONS: The experiment results show that the proposed method can segment various small GGO pulmonary nodules more accurately and robustly, which is helpful for the accurate evaluation of medical imaging.
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Traitement d'image par ordinateur / Chaines de Markov / Tumeurs du poumon Type d'étude: Clinical_trials / Health_economic_evaluation / Prognostic_studies / Screening_studies Limites: Adult / Female / Humans / Male Langue: En Journal: Biomed Eng Online Sujet du journal: ENGENHARIA BIOMEDICA Année: 2020 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Traitement d'image par ordinateur / Chaines de Markov / Tumeurs du poumon Type d'étude: Clinical_trials / Health_economic_evaluation / Prognostic_studies / Screening_studies Limites: Adult / Female / Humans / Male Langue: En Journal: Biomed Eng Online Sujet du journal: ENGENHARIA BIOMEDICA Année: 2020 Type de document: Article Pays d'affiliation: Chine Pays de publication: Royaume-Uni