Overview of Covid-19 Regarding the Cardiovascular Situation in the Light of Current Reports.
Cardiovasc Hematol Disord Drug Targets
; 20(3): 181-184, 2020.
Article
de En
| MEDLINE
| ID: mdl-32611305
ABSTRACT
Nowadays Coronavirus Disease 2019 (Covid-19) is increasing mortality all over the world mercilessly. We are learning almost every day about its new symptoms and that it mutates quickly. This disease has tied us up and made us desperate. The death rate from this disease has increased in patients who had pre-existing medical conditions, especially cardiovascular ones, by eliminating the angiotensin-converting enzyme (ACE)-2 receptor in the lungs. Also, ACE1 and angiotensin receptor blockers (ARB) may stimulate ACE2 expression and worse the prognosis. Intravenous infusions of ACEIs and ARBs in experimental animals increase the number of ACE2 receptors. Therefore, it may be one of the reasons that COVID-19 infects the cells of patients treating hypertension. However, most of the congress of cardiology do not recommend to discontinue these anti-hypertensive drugs. Therefore, this brief report evaluates Covid-19 in the view of cardiovascular diseases taking into account current reports and suggests some possible solutions to keep the virus under control.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Inhibiteurs de l'enzyme de conversion de l'angiotensine
/
Maladies cardiovasculaires
/
Antagonistes des récepteurs aux angiotensines
/
COVID-19
Type d'étude:
Etiology_studies
/
Prognostic_studies
Limites:
Animals
/
Humans
Langue:
En
Journal:
Cardiovasc Hematol Disord Drug Targets
Sujet du journal:
ANGIOLOGIA
/
CARDIOLOGIA
/
HEMATOLOGIA
/
TERAPIA POR MEDICAMENTOS
Année:
2020
Type de document:
Article
Pays d'affiliation:
Turquie