Enhancer-gene rewiring in the pathogenesis of Quebec platelet disorder.

Liang, Minggao; Soomro, Asim; Tasneem, Subia; Abatti, Luis E; Alizada, Azad; Yuan, Xuefei; Uusküla-Reimand, Liis; Antounians, Lina; Alvi, Sana Akhtar; Paterson, Andrew D; Rivard, Georges-Étienne; Scott, Ian C; Mitchell, Jennifer A; Hayward, Catherine P M; Wilson, Michael D

Liang, Minggao; Soomro, Asim; Tasneem, Subia; Abatti, Luis E; Alizada, Azad; Yuan, Xuefei; Uusküla-Reimand, Liis; Antounians, Lina; Alvi, Sana Akhtar; Paterson, Andrew D; Rivard, Georges-Étienne; Scott, Ian C; Mitchell, Jennifer A; Hayward, Catherine P M; Wilson, Michael D.

Affiliation

Liang M; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Soomro A; Department of Molecular Genetics, The University of Toronto, Toronto, ON, Canada.
Tasneem S; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Abatti LE; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
Alizada A; Department of Cell and Systems Biology and.
Yuan X; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Uusküla-Reimand L; Department of Molecular Genetics, The University of Toronto, Toronto, ON, Canada.
Antounians L; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Alvi SA; Department of Molecular Genetics, The University of Toronto, Toronto, ON, Canada.
Paterson AD; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Rivard GÉ; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Scott IC; Department of Molecular Genetics, The University of Toronto, Toronto, ON, Canada.
Mitchell JA; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Hayward CPM; Program in Genetics and Genome Biology, SickKids Research Institute, Toronto, ON, Canada.
Wilson MD; Dalla Lana School of Public Health and Institute of Medical Sciences, The University of Toronto, ON, Canada.

Blood ; 136(23): 2679-2690, 2020 12 03.

Article de En | MEDLINE | ID: mdl-32663239

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Mégacaryocytes / Régulation de l'expression des gènes / Éléments activateurs (génétique) / Duplication de gène / Déficit en facteur V / Protéines membranaires Type d'étude: Etiology_studies Limites: Animals / Female / Humans Langue: En Journal: Blood Année: 2020 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique

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