Synthesis and Anticancer Activity of Dimeric Polyether Ionophores.

Sulik, Michal; Maj, Ewa; Wietrzyk, Joanna; Huczynski, Adam; Antoszczak, Michal

Sulik, Michal; Maj, Ewa; Wietrzyk, Joanna; Huczynski, Adam; Antoszczak, Michal.

Affiliation

Sulik M; Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland.
Maj E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wroclaw, Poland.
Wietrzyk J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Rudolfa Weigla 12, 53-114 Wroclaw, Poland.
Huczynski A; Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland.
Antoszczak M; Department of Medical Chemistry, Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznanskiego 8, 61-614 Poznan, Poland.

Biomolecules ; 10(7)2020 07 12.

Article de En | MEDLINE | ID: mdl-32664671

Sujet(s)
Mots clés

Huisgen 1,3-dipolar cycloaddition; SAR analysis; antiproliferative activity; betulinic acid; in vitro assay; multi-drug resistance; polyether ionophores; stereoselective reactions; tumor-specificity; 'click' chemistry

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Éthers / Ionophores / Antinéoplasiques Limites: Humans Langue: En Journal: Biomolecules Année: 2020 Type de document: Article Pays d'affiliation: Pologne Pays de publication: Suisse

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