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Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
Sobolova, Katerina; Hrabinova, Martina; Hepnarova, Vendula; Kucera, Tomas; Kobrlova, Tereza; Benkova, Marketa; Janockova, Jana; Dolezal, Rafael; Prchal, Lukas; Benek, Ondrej; Mezeiova, Eva; Jun, Daniel; Soukup, Ondrej; Korabecny, Jan.
Affiliation
  • Sobolova K; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic.
  • Hrabinova M; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Soko
  • Hepnarova V; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic.
  • Kucera T; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic.
  • Kobrlova T; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Soko
  • Benkova M; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Janockova J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Dolezal R; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.
  • Prchal L; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Benek O; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Mezeiova E; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.
  • Jun D; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Soko
  • Soukup O; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Soko
  • Korabecny J; Department of Toxicology and Military Pharmacy, Department of Military Medical Service Organisation and Management, Faculty of Military Health Sciences, University of Defense, Trebesska 1575, 500 05, Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Soko
Eur J Med Chem ; 203: 112593, 2020 Oct 01.
Article de En | MEDLINE | ID: mdl-32688201
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Berbérine / Conception de médicament / Anticholinestérasiques / Cholinesterases / Prolyl-oligopeptidases Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2020 Type de document: Article Pays d'affiliation: République tchèque Pays de publication: France
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Berbérine / Conception de médicament / Anticholinestérasiques / Cholinesterases / Prolyl-oligopeptidases Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2020 Type de document: Article Pays d'affiliation: République tchèque Pays de publication: France