Comparative genomic insights into Yersinia hibernica - a commonly misidentified Yersinia enterocolitica-like organism.
Microb Genom
; 6(9)2020 09.
Article
de En
| MEDLINE
| ID: mdl-32701425
ABSTRACT
Food-associated outbreaks linked to enteropathogenic Yersinia enterocolitica are of concern to public health. Pigs and their meat are recognized risk factors for transmission of Y. enterocolitica. This study aimed to describe the comparative genomics of Y. enterocolitica along with a number of misclassified Yersinia isolates, now constituting the recently described Yersinia hibernica. The latter was originally cultured from an environmental sample taken at a pig slaughterhouse. Unique features were identified in the genome of Y. hibernica, including a novel integrative conjugative element (ICE), denoted as ICEYh-1 contained within a 255 kbp region of plasticity. In addition, a zebrafish embryo infection model was adapted and applied to assess the virulence potential among Yersinia isolates including Y. hibernica.
Mots clés
Texte intégral:
1
Collection:
01-internacional
Base de données:
MEDLINE
Sujet principal:
Yersinia
/
Yersinia enterocolitica
/
Yersinioses
/
Génomique
/
Embryon non mammalien
Type d'étude:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
Limites:
Animals
Langue:
En
Journal:
Microb Genom
Année:
2020
Type de document:
Article
Pays d'affiliation:
Irlande