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Discovery of novel small molecule inhibitors of S100P with in vitro anti-metastatic effects on pancreatic cancer cells.
Camara, Ramatoulie; Ogbeni, Deborah; Gerstmann, Lisa; Ostovar, Mehrnoosh; Hurer, Ellie; Scott, Mark; Mahmoud, Nasir G; Radon, Tomasz; Crnogorac-Jurcevic, Tatjana; Patel, Pryank; Mackenzie, Louise S; Chau, David Y S; Kirton, Stewart B; Rossiter, Sharon.
Affiliation
  • Camara R; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Ogbeni D; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Gerstmann L; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Ostovar M; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Hurer E; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Scott M; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Mahmoud NG; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
  • Radon T; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
  • Crnogorac-Jurcevic T; Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK.
  • Patel P; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Mackenzie LS; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK; School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, BN2 4GJ, UK.
  • Chau DYS; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK; Eastman Dental Institute, University College London, 256 Grays Inn Rd, London, WC1X 8LD, UK.
  • Kirton SB; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK.
  • Rossiter S; School of Life and Medical Sciences, University of Hertfordshire, Hatfield, AL10 9AB, UK. Electronic address: s.rossiter@herts.ac.uk.
Eur J Med Chem ; 203: 112621, 2020 Oct 01.
Article de En | MEDLINE | ID: mdl-32707527

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du pancréas / Conception de médicament / Protéines S100 / Bibliothèques de petites molécules / Antinéoplasiques Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2020 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: France

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du pancréas / Conception de médicament / Protéines S100 / Bibliothèques de petites molécules / Antinéoplasiques Limites: Humans Langue: En Journal: Eur J Med Chem Année: 2020 Type de document: Article Pays d'affiliation: Royaume-Uni Pays de publication: France