NRF2 mediates Î³-globin gene regulation through epigenetic modifications in a ß-YAC transgenic mouse model.

Zhu, Xingguo; Xi, Caixia; Ward, Alexander; Takezaki, Mayuko; Shi, Huidong; Peterson, Kenneth R; Pace, Betty S

Zhu, Xingguo; Xi, Caixia; Ward, Alexander; Takezaki, Mayuko; Shi, Huidong; Peterson, Kenneth R; Pace, Betty S.

Affiliation

Zhu X; Division of Hematology/Oncology, Department of Pediatrics, Augusta University, Augusta, GA 30912, USA.
Xi C; Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
Ward A; Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
Takezaki M; Division of Hematology/Oncology, Department of Pediatrics, Augusta University, Augusta, GA 30912, USA.
Shi H; Division of Hematology/Oncology, Department of Pediatrics, Augusta University, Augusta, GA 30912, USA.
Peterson KR; Georgia Cancer Center, Augusta University, Augusta, GA 30912, USA.
Pace BS; Department of Biochemistry and Molecular Biology, University of Kansas Medical Center, Kansas City, KS 66160, USA.

Exp Biol Med (Maywood) ; 245(15): 1308-1318, 2020 09.

Article de En | MEDLINE | ID: mdl-32715783

Sujet(s)
Mots clés

NRF2; chromatin; epigenetic modification; fetal hemoglobin; ß-YAC mouse

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Chromosomes artificiels de levure / Épigenèse génétique / Facteur-2 apparenté à NF-E2 / Globines gamma Type d'étude: Prognostic_studies Limites: Animals / Female / Humans / Male Langue: En Journal: Exp Biol Med (Maywood) Sujet du journal: BIOLOGIA / FISIOLOGIA / MEDICINA Année: 2020 Type de document: Article Pays d'affiliation: États-Unis d'Amérique Pays de publication: Royaume-Uni

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