Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.

Zhang, Yueping; Holenarsipur, Vinay K; Kandoussi, Hamza; Zeng, Jianing; Mariappan, T Thanga; Sinz, Michael; Shen, Hong

Zhang, Yueping; Holenarsipur, Vinay K; Kandoussi, Hamza; Zeng, Jianing; Mariappan, T Thanga; Sinz, Michael; Shen, Hong.

Affiliation

Zhang Y; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Holenarsipur VK; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Kandoussi H; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Zeng J; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Mariappan TT; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Sinz M; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa
Shen H; Departments of Metabolism and Pharmacokinetics (Y.Z., M.S., H.S.) and Bioanalytical Sciences (H.K., J.Z.), Bristol Myers Squibb Company, Princeton, New Jersey; and Departments of Metabolism and Pharmacokinetics (V.K.H., T.T.M.), Biocon Bristol Myers Squibb R&D Centre (BBRC), Syngene Internationa

Drug Metab Dispos ; 48(10): 841-848, 2020 10.

Article de En | MEDLINE | ID: mdl-32723847

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Probénécide / Polypeptide C de transport d'anions organiques / Membre 1B3 de la famille des transporteurs d'anions organiques appartenant aux transporteurs de solutés Type d'étude: Diagnostic_studies / Prognostic_studies Limites: Female / Humans / Male Langue: En Journal: Drug Metab Dispos Sujet du journal: FARMACOLOGIA Année: 2020 Type de document: Article Pays de publication: États-Unis d'Amérique

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