The gut microbiome switches mutant p53 from tumour-suppressive to oncogenic.

Kadosh, Eliran; Snir-Alkalay, Irit; Venkatachalam, Avanthika; May, Shahaf; Lasry, Audrey; Elyada, Ela; Zinger, Adar; Shaham, Maya; Vaalani, Gitit; Mernberger, Marco; Stiewe, Thorsten; Pikarsky, Eli; Oren, Moshe; Ben-Neriah, Yinon

Kadosh, Eliran; Snir-Alkalay, Irit; Venkatachalam, Avanthika; May, Shahaf; Lasry, Audrey; Elyada, Ela; Zinger, Adar; Shaham, Maya; Vaalani, Gitit; Mernberger, Marco; Stiewe, Thorsten; Pikarsky, Eli; Oren, Moshe; Ben-Neriah, Yinon.

Affiliation

Kadosh E; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Snir-Alkalay I; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Venkatachalam A; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
May S; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Lasry A; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Elyada E; Department of Pathology, New York University School of Medicine, New York, NY, USA.
Zinger A; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Shaham M; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.
Vaalani G; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Mernberger M; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Stiewe T; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Pikarsky E; Institute of Molecular Oncology, Genomics Core Facility, Philipps University Marburg, Marburg, Germany.
Oren M; Institute of Molecular Oncology, Genomics Core Facility, Philipps University Marburg, Marburg, Germany.
Ben-Neriah Y; The Lautenberg Center for Immunology and Cancer Research, Institute of Medical Research Israel-Canada, Hebrew University-Hadassah Medical School, Jerusalem, Israel.

Nature ; 586(7827): 133-138, 2020 10.

Article de En | MEDLINE | ID: mdl-32728212

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Oncogènes / Gènes suppresseurs de tumeur / Protéine p53 suppresseur de tumeur / Carcinogenèse / Microbiome gastro-intestinal / Mutation Limites: Animals / Female / Humans / Male Langue: En Journal: Nature Année: 2020 Type de document: Article Pays d'affiliation: Israël Pays de publication: Royaume-Uni

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