PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance.

Montaudon, Elodie; Nikitorowicz-Buniak, Joanna; Sourd, Laura; Morisset, Ludivine; El Botty, Rania; Huguet, Léa; Dahmani, Ahmed; Painsec, Pierre; Nemati, Fariba; Vacher, Sophie; Chemlali, Walid; Masliah-Planchon, Julien; Château-Joubert, Sophie; Rega, Camilla; Leal, Mariana Ferreira; Simigdala, Nikiana; Pancholi, Sunil; Ribas, Ricardo; Nicolas, André; Meseure, Didier; Vincent-Salomon, Anne; Reyes, Cécile; Rapinat, Audrey; Gentien, David; Larcher, Thibaut; Bohec, Mylène; Baulande, Sylvain; Bernard, Virginie; Decaudin, Didier; Coussy, Florence; Le Romancer, Muriel; Dutertre, Guillaume; Tariq, Zakia; Cottu, Paul; Driouch, Keltouma; Bièche, Ivan; Martin, Lesley-Ann; Marangoni, Elisabetta

Montaudon, Elodie; Nikitorowicz-Buniak, Joanna; Sourd, Laura; Morisset, Ludivine; El Botty, Rania; Huguet, Léa; Dahmani, Ahmed; Painsec, Pierre; Nemati, Fariba; Vacher, Sophie; Chemlali, Walid; Masliah-Planchon, Julien; Château-Joubert, Sophie; Rega, Camilla; Leal, Mariana Ferreira; Simigdala, Nikiana; Pancholi, Sunil; Ribas, Ricardo; Nicolas, André; Meseure, Didier; Vincent-Salomon, Anne; Reyes, Cécile; Rapinat, Audrey; Gentien, David; Larcher, Thibaut; Bohec, Mylène; Baulande, Sylvain; Bernard, Virginie; Decaudin, Didier; Coussy, Florence; Le Romancer, Muriel; Dutertre, Guillaume; Tariq, Zakia; Cottu, Paul; Driouch, Keltouma; Bièche, Ivan; Martin, Lesley-Ann; Marangoni, Elisabetta.

Affiliation

Montaudon E; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Nikitorowicz-Buniak J; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Sourd L; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Morisset L; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
El Botty R; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Huguet L; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Dahmani A; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Painsec P; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Nemati F; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Vacher S; Department of Genetics, Institut Curie, Paris, France.
Chemlali W; Department of Genetics, Institut Curie, Paris, France.
Masliah-Planchon J; Department of Genetics, Institut Curie, Paris, France.
Château-Joubert S; Alfort Veterinary School, 7 Av. Du Général-de-Gaulle, 94000, Maisons-Alfort, France.
Rega C; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Leal MF; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Simigdala N; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Pancholi S; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Ribas R; Institute of Cancer Research, 123 Old Brompton Road, SW7 3RP, London, UK.
Nicolas A; Department of Pathology, Institut Curie, Paris, France.
Meseure D; Department of Pathology, Institut Curie, Paris, France.
Vincent-Salomon A; Department of Pathology, Institut Curie, Paris, France.
Reyes C; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Rapinat A; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Gentien D; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Larcher T; INRA, APEX-PAnTher, Oniris, Rue De La Géraudière Cedex 3, 44322, Nantes, France.
Bohec M; Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Baulande S; Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.
Bernard V; Department of Genetics, Institut Curie, Paris, France.
Decaudin D; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Coussy F; Department of Medical Oncology, Institut Curie, Paris, France.
Le Romancer M; Translational Research Department, Institut Curie, 26 Rue d'Ulm, 75005, Paris, France.
Dutertre G; Department of Medical Oncology, Institut Curie, Paris, France.
Tariq Z; Inserm U1052, Centre de Recherche en Cancérologie de Lyon, 28 Rue Laennec, 69000, Lyon, France.
Cottu P; Department of Surgery, Institut Curie, Paris, France.
Driouch K; Department of Genetics, Institut Curie, Paris, France.
Bièche I; Department of Medical Oncology, Institut Curie, Paris, France.
Martin LA; Department of Genetics, Institut Curie, Paris, France.
Marangoni E; Department of Genetics, Institut Curie, Paris, France.

Nat Commun ; 11(1): 4053, 2020 08 13.

Article de En | MEDLINE | ID: mdl-32792481

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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Tumeurs du sein / Protéines proto-oncogènes / Protein-Serine-Threonine Kinases / Protéines du cycle cellulaire / Cycline D1 / Limites: Animals / Humans Langue: En Journal: Nat Commun Sujet du journal: BIOLOGIA / CIENCIA Année: 2020 Type de document: Article Pays d'affiliation: France

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