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Metformin promotes CNS remyelination and improves social interaction following focal demyelination through CBP Ser436 phosphorylation.
Kosaraju, Jayasankar; Seegobin, Matthew; Gouveia, Ayden; Syal, Charvi; Sarma, Sailendra Nath; Lu, Kevin Jiaqi; Ilin, Julius; He, Ling; Wondisford, Fredric E; Lagace, Diane; De Repentigny, Yves; Kothary, Rashmi; Wang, Jing.
Affiliation
  • Kosaraju J; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Seegobin M; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Gouveia A; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Syal C; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada.
  • Sarma SN; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Lu KJ; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Ilin J; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • He L; Department of Pediatrics and Medicine, Johns Hopkins Medical School, Baltimore, MD 21287, USA.
  • Wondisford FE; Department of Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.
  • Lagace D; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON K1H 8M5, Canada; Canadian Partnership for Stroke Recovery, Ottawa, ON K1G 5Z3, Canada.
  • De Repentigny Y; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada.
  • Kothary R; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON K1H 8M5, Canada; Dep
  • Wang J; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, ON K1H 8L6, Canada; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada; University of Ottawa Brain and Mind Research Institute, Ottawa, ON K1H 8M5, Canada; Can
Exp Neurol ; 334: 113454, 2020 12.
Article de En | MEDLINE | ID: mdl-32877653
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Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladies démyélinisantes / Histone acetyltransferases / Remyélinisation / Interaction sociale / Metformine Limites: Animals Langue: En Journal: Exp Neurol Année: 2020 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique
Texte intégral
Ajouter à My VHL
Imprimer
XML
PubMed Links
Recherche sur Google

Texte intégral: 1 Collection: 01-internacional Base de données: MEDLINE Sujet principal: Maladies démyélinisantes / Histone acetyltransferases / Remyélinisation / Interaction sociale / Metformine Limites: Animals Langue: En Journal: Exp Neurol Année: 2020 Type de document: Article Pays d'affiliation: Canada Pays de publication: États-Unis d'Amérique